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Stable membrane orientations of small dual-topology membrane proteins

The topologies of α-helical membrane proteins are generally thought to be determined during their cotranslational insertion into the membrane. It is typically assumed that membrane topologies remain static after this process has ended. Recent findings, however, question this static view by suggestin...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Fluman, Nir, Tobiasson, Victor, von Heijne, Gunnar
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544329/
https://ncbi.nlm.nih.gov/pubmed/28698365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706905114
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