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Stable membrane orientations of small dual-topology membrane proteins

The topologies of α-helical membrane proteins are generally thought to be determined during their cotranslational insertion into the membrane. It is typically assumed that membrane topologies remain static after this process has ended. Recent findings, however, question this static view by suggestin...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Fluman, Nir, Tobiasson, Victor, von Heijne, Gunnar
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544329/
https://ncbi.nlm.nih.gov/pubmed/28698365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706905114
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