Caffeine induces gastric acid secretion via bitter taste signaling in gastric parietal cells

Caffeine, generally known as a stimulant of gastric acid secretion (GAS), is a bitter-tasting compound that activates several taste type 2 bitter receptors (TAS2Rs). TAS2Rs are expressed in the mouth and in several extraoral sites, e.g., in the gastrointestinal tract, in which their functional role...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Liszt, Kathrin Ingrid, Ley, Jakob Peter, Lieder, Barbara, Behrens, Maik, Stöger, Verena, Reiner, Angelika, Hochkogler, Christina Maria, Köck, Elke, Marchiori, Alessandro, Hans, Joachim, Widder, Sabine, Krammer, Gerhard, Sanger, Gareth John, Somoza, Mark Manuel, Meyerhof, Wolfgang, Somoza, Veronika
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544304/
https://ncbi.nlm.nih.gov/pubmed/28696284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703728114
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