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Stem cell-released oncolytic herpes simplex virus has therapeutic efficacy in brain metastatic melanomas

The recent Food and Drug Administration approval of immunogenic oncolytic virus (OV) has opened a new era in the treatment of advanced melanoma; however, approximately 50% of patients with melanoma develop brain metastasis, and currently there are no beneficial treatment options for such patients. T...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Du, Wanlu, Seah, Ivan, Bougazzoul, Oumaima, Choi, GiHun, Meeth, Katrina, Bosenberg, Marcus W., Wakimoto, Hiroaki, Fisher, David, Shah, Khalid
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544283/
https://ncbi.nlm.nih.gov/pubmed/28710334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700363114
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