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MmpL3 is the flippase for mycolic acids in mycobacteria

The defining feature of the mycobacterial outer membrane (OM) is the presence of mycolic acids (MAs), which, in part, render the bilayer extremely hydrophobic and impermeable to external insults, including many antibiotics. Although the biosynthetic pathway of MAs is well studied, the mechanism(s) b...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Xu, Zhujun, Meshcheryakov, Vladimir A., Poce, Giovanna, Chng, Shu-Sin
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544280/
https://ncbi.nlm.nih.gov/pubmed/28698380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700062114
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