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MmpL3 is the flippase for mycolic acids in mycobacteria

The defining feature of the mycobacterial outer membrane (OM) is the presence of mycolic acids (MAs), which, in part, render the bilayer extremely hydrophobic and impermeable to external insults, including many antibiotics. Although the biosynthetic pathway of MAs is well studied, the mechanism(s) b...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Xu, Zhujun, Meshcheryakov, Vladimir A., Poce, Giovanna, Chng, Shu-Sin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544280/
https://ncbi.nlm.nih.gov/pubmed/28698380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700062114
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