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PKC-epsilon deficiency alters progenitor cell populations in favor of megakaryopoiesis

BACKGROUND: It has long been postulated that Protein Kinase C (PKC) is an important regulator of megakaryopoiesis. Recent contributions to the literature have outlined the functions of several individual PKC isoforms with regard to megakaryocyte differentiation and platelet production. However, the...

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Publicat a:PLoS One
Autors principals: Kostyak, John C., Liverani, Elisabetta, Kunapuli, Satya P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544228/
https://ncbi.nlm.nih.gov/pubmed/28783756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182867
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