Erythroid-specific expression of human beta-globin genes in transgenic mice.

Transgenic mice carrying human beta-globin genes were produced by microinjecting linear DNA molecules containing cloned beta-globin genes with up to 4300 bp of 5'-flanking sequence and 1700 bp of 3'-flanking sequence. Most (15 of 20) of these transgenic mice expressed the human beta-globin...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Townes, T M, Lingrel, J B, Chen, H Y, Brinster, R L, Palmiter, R D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554408/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2992937/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1985.tb03841.x
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