Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI

BACKGROUND. Dysregulated lipid and glucose metabolism in clear cell renal cell carcinoma (ccRCC) has been implicated in disease progression, and whole tumor tissue–based assessment of these changes is challenged by the tumor heterogeneity. We studied a noninvasive quantitative MRI method that predic...

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Udgivet i:JCI Insight
Main Authors: Zhang, Yue, Udayakumar, Durga, Cai, Ling, Hu, Zeping, Kapur, Payal, Kho, Eun-Young, Pavía-Jiménez, Andrea, Fulkerson, Michael, de Leon, Alberto Diaz, Yuan, Qing, Dimitrov, Ivan E., Yokoo, Takeshi, Ye, Jin, Mitsche, Matthew A., Kim, Hyeonwoo, McDonald, Jeffrey G., Xi, Yin, Madhuranthakam, Ananth J., Dwivedi, Durgesh K., Lenkinski, Robert E., Cadeddu, Jeffrey A., Margulis, Vitaly, Brugarolas, James, DeBerardinis, Ralph J., Pedrosa, Ivan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2017
Fag:
Clinical Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543910/
https://ncbi.nlm.nih.gov/pubmed/28768909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94278
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