Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI

BACKGROUND. Dysregulated lipid and glucose metabolism in clear cell renal cell carcinoma (ccRCC) has been implicated in disease progression, and whole tumor tissue–based assessment of these changes is challenged by the tumor heterogeneity. We studied a noninvasive quantitative MRI method that predic...

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Pubblicato in:JCI Insight
Autori principali: Zhang, Yue, Udayakumar, Durga, Cai, Ling, Hu, Zeping, Kapur, Payal, Kho, Eun-Young, Pavía-Jiménez, Andrea, Fulkerson, Michael, de Leon, Alberto Diaz, Yuan, Qing, Dimitrov, Ivan E., Yokoo, Takeshi, Ye, Jin, Mitsche, Matthew A., Kim, Hyeonwoo, McDonald, Jeffrey G., Xi, Yin, Madhuranthakam, Ananth J., Dwivedi, Durgesh K., Lenkinski, Robert E., Cadeddu, Jeffrey A., Margulis, Vitaly, Brugarolas, James, DeBerardinis, Ralph J., Pedrosa, Ivan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2017
Soggetti:
Clinical Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543910/
https://ncbi.nlm.nih.gov/pubmed/28768909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94278
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