Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI

BACKGROUND. Dysregulated lipid and glucose metabolism in clear cell renal cell carcinoma (ccRCC) has been implicated in disease progression, and whole tumor tissue–based assessment of these changes is challenged by the tumor heterogeneity. We studied a noninvasive quantitative MRI method that predic...

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Publicado en:JCI Insight
Main Authors: Zhang, Yue, Udayakumar, Durga, Cai, Ling, Hu, Zeping, Kapur, Payal, Kho, Eun-Young, Pavía-Jiménez, Andrea, Fulkerson, Michael, de Leon, Alberto Diaz, Yuan, Qing, Dimitrov, Ivan E., Yokoo, Takeshi, Ye, Jin, Mitsche, Matthew A., Kim, Hyeonwoo, McDonald, Jeffrey G., Xi, Yin, Madhuranthakam, Ananth J., Dwivedi, Durgesh K., Lenkinski, Robert E., Cadeddu, Jeffrey A., Margulis, Vitaly, Brugarolas, James, DeBerardinis, Ralph J., Pedrosa, Ivan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2017
Assuntos:
Clinical Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543910/
https://ncbi.nlm.nih.gov/pubmed/28768909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94278
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