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Atypical Antipsychotics and Inverse Agonism at 5-HT(2) Receptors

It is now well accepted that receptors can regulate cellular signaling pathways in the absence of a stimulating ligand, and inverse agonists can reduce this ligand-independent or “constitutive” receptor activity. Both the serotonin 5-HT(2A) and 5-HT(2C) receptors have demonstrated constitutive recep...

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Detalles Bibliográficos
Publicado en:Curr Pharm Des
Main Authors: Sullivan, Laura C., Clarke, William P., Berg, Kelly A.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543701/
https://ncbi.nlm.nih.gov/pubmed/26044975
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