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Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity

Constitutive receptor activity/inverse agonism and functional selectivity/biased agonism are 2 concepts in contemporary pharmacology that have major implications for the use of drugs in medicine and research as well as for the processes of new drug development. Traditional receptor theory postulated...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Berg, Kelly A, Clarke, William P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165953/
https://ncbi.nlm.nih.gov/pubmed/30085126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyy071
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