Safety and Antitumor Activity of Apalutamide (ARN-509) in Metastatic Castration-Resistant Prostate Cancer Patients with and without Prior Abiraterone Acetate and Prednisone

PURPOSE: To evaluate the efficacy of apalutamide before or after treatment with abiraterone acetate and prednisone (AAP) in patients with progressive metastatic castration-resistant prostate cancer (mCRPC). EXPERIMENTAL DESIGN: Two cohorts were studied: AAP-naïve and post-AAP patients who had receiv...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Rathkopf, Dana E., Antonarakis, Emmanuel S., Shore, Neal D., Tutrone, Ronald F., Alumkal, Joshi J., Ryan, Charles J., Saleh, Mansoor, Hauke, Ralph J., Bandekar, Rajesh, Maneval, Edna Chow, de Boer, Carla J., Yu, Margaret K., Scher, Howard I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543693/
https://ncbi.nlm.nih.gov/pubmed/28213364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2509
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