Safety and Antitumor Activity of Apalutamide (ARN-509) in Metastatic Castration-Resistant Prostate Cancer Patients with and without Prior Abiraterone Acetate and Prednisone

PURPOSE: To evaluate the efficacy of apalutamide before or after treatment with abiraterone acetate and prednisone (AAP) in patients with progressive metastatic castration-resistant prostate cancer (mCRPC). EXPERIMENTAL DESIGN: Two cohorts were studied: AAP-naïve and post-AAP patients who had receiv...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Rathkopf, Dana E., Antonarakis, Emmanuel S., Shore, Neal D., Tutrone, Ronald F., Alumkal, Joshi J., Ryan, Charles J., Saleh, Mansoor, Hauke, Ralph J., Bandekar, Rajesh, Maneval, Edna Chow, de Boer, Carla J., Yu, Margaret K., Scher, Howard I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543693/
https://ncbi.nlm.nih.gov/pubmed/28213364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2509
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