Safety and Antitumor Activity of Apalutamide (ARN-509) in Metastatic Castration-Resistant Prostate Cancer Patients with and without Prior Abiraterone Acetate and Prednisone

PURPOSE: To evaluate the efficacy of apalutamide before or after treatment with abiraterone acetate and prednisone (AAP) in patients with progressive metastatic castration-resistant prostate cancer (mCRPC). EXPERIMENTAL DESIGN: Two cohorts were studied: AAP-naïve and post-AAP patients who had receiv...

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Опубликовано в: :Clin Cancer Res
Главные авторы: Rathkopf, Dana E., Antonarakis, Emmanuel S., Shore, Neal D., Tutrone, Ronald F., Alumkal, Joshi J., Ryan, Charles J., Saleh, Mansoor, Hauke, Ralph J., Bandekar, Rajesh, Maneval, Edna Chow, de Boer, Carla J., Yu, Margaret K., Scher, Howard I.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543693/
https://ncbi.nlm.nih.gov/pubmed/28213364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2509
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