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Androgen receptor mutations in patients with castration-resistant prostate cancer treated with apalutamide
BACKGROUND: Mutations in the androgen receptor (AR) ligand-binding domain (LBD), such as F877L and T878A, have been associated with resistance to next-generation AR-directed therapies. ARN-509-001 was a phase I/II study that evaluated apalutamide activity in castration-resistant prostate cancer (CRP...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Ann Oncol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5834046/ https://ncbi.nlm.nih.gov/pubmed/28633425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdx283 |
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