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CTLA‐4 expressed by FOXP3(+) regulatory T cells prevents inflammatory tissue attack and not T‐cell priming in arthritis
Cytotoxic T‐lymphocyte antigen 4 (CTLA‐4) ‐mediated regulation of already tolerized autoreactive T cells is critical for understanding autoimmune responses. Although defects in CTLA‐4 contribute to abnormal FOXP3(+) regulatory T (Treg) cell function in rheumatoid arthritis, its role in autoreactive...
Guardat en:
| Publicat a: | Immunology |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5543501/ https://ncbi.nlm.nih.gov/pubmed/28497863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12754 |
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