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Imaging regulatory T cell dynamics and suppression of T cell priming mediated by CTLA4

Foxp3(+) regulatory T cells (Tregs) maintain immune homeostasis through mechanisms that remain incompletely defined. Here, by two-photon imaging, we examine the cellular dynamics of endogenous Tregs. Tregs are identified as two non-overlapping populations in the T-zone and follicular regions of the...

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Detalhes bibliográficos
Publicado no:Nat Commun
Principais autores: Matheu, Melanie P., Othy, Shivashankar, Greenberg, Milton L., Dong, Tobias X., Schuijs, Martijn, Deswarte, Kim, Hammad, Hamida, Lambrecht, Bart N., Parker, Ian, Cahalan, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347855/
https://ncbi.nlm.nih.gov/pubmed/25653051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7219
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