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Tumour‐associated changes in intestinal epithelial cells cause local accumulation of KLRG1(+) GATA3(+) regulatory T cells in mice

CD4(+) Foxp3(+) regulatory T (Treg) cells include differentiated populations of effector Treg cells characterized by the expression of specific transcription factors. Tumours, including intestinal malignancies, often present with local accumulation of Treg cells that can prevent tumour clearance, bu...

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Vydáno v:Immunology
Hlavní autoři: Meinicke, Holger, Bremser, Anna, Brack, Maria, Akeus, Paulina, Pearson, Claire, Bullers, Samuel, Hoffmeyer, Katrin, Stemmler, Marc P., Quiding‐Järbrink, Marianne, Izcue, Ana
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543491/
https://ncbi.nlm.nih.gov/pubmed/28437001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12750
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