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Modulation of activation and inactivation by Ca(2+) and 2-APB in the pore of an archetypal TRPM channel from Nematostella vectensis

The archetypal TRPM2-like channel of the sea anemone Nematostella vectensis is gated by ADPR like its human orthologue but additionally exhibits properties of other vertebrate TRPM channels. Thus it can help towards an understanding of gating and regulation of the whole subfamily. To elucidate furth...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kühn, Frank J. P., Mathis, Winking, Cornelia, Kühn, Hoffmann, Daniel C., Lückhoff, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543165/
https://ncbi.nlm.nih.gov/pubmed/28775320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07652-4
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