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Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents
The Ca(2+)-permeable cation channel transient receptor potential melastatin 2 (TRPM2) plays a key role in pathogen-evoked phagocyte activation, postischemic neuronal apoptosis, and glucose-evoked insulin secretion, by linking these cellular responses to oxidative stress. TRPM2 channels are coactivat...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3421201/ https://ncbi.nlm.nih.gov/pubmed/22847436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204702109 |
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