Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells

Human endothelial cells are initiators and targets of the rejection response. Pre-operative modification of endothelial cells by small interfering RNA transfection could shape the nature of the host response post-transplantation. Ablation of endothelial cell class II major histocompatibility complex...

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Vydáno v:Nat Commun
Hlavní autoři: Cui, Jiajia, Qin, Lingfeng, Zhang, Junwei, Abrahimi, Parwiz, Li, Hong, Li, Guangxin, Tietjen, Gregory T., Tellides, George, Pober, Jordan S., Mark Saltzman, W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543113/
https://ncbi.nlm.nih.gov/pubmed/28775323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00297-x
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