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In silico model of the human ClC-Kb chloride channel: pore mapping, biostructural pathology and drug screening
The human ClC-Kb channel plays a key role in exporting chloride ions from the cytosol and is known to be involved in Bartter syndrome type 3 when its permeation capacity is decreased. The ClC-Kb channel has been recently proposed as a potential therapeutic target to treat hypertension. In order to g...
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| Publicado no: | Sci Rep |
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| Principais autores: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5543074/ https://ncbi.nlm.nih.gov/pubmed/28775266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07794-5 |
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