ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells

The concept that tumor-initiating cells can co-opt the self-renewal program of endogenous stem cells as a means of enforcing their unlimited proliferative potential is widely accepted, yet identification of specific factors that regulate self-renewal of normal and cancer stem cells remains limited....

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Udgivet i:Blood
Main Authors: Garrison, Brian S., Rybak, Adrian P., Beerman, Isabel, Heesters, Balthasar, Mercier, Francois E., Scadden, David T., Bryder, David, Baron, Roland, Rossi, Derrick J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542850/
https://ncbi.nlm.nih.gov/pubmed/28615219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-09-738591
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