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Type 1-skewed neuroinflammation and vascular damage associated with Orientia tsutsugamushi infection in mice

BACKGROUND: Scrub typhus is a life-threatening disease, due to infection with O. tsutsugamushi, a Gram-negative bacterium that preferentially replicates in endothelial cells and professional phagocytes. Meningoencephalitis has been reported in scrub typhus patients and experimentally-infected animal...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Soong, Lynn, Shelite, Thomas R., Xing, Yan, Kodakandla, Harica, Liang, Yuejin, Trent, Brandon J., Horton, Paulina, Smith, Kathryn C., Zhao, Zhenyang, Sun, Jiaren, Bouyer, Donald H., Cai, Jiyang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542690/
https://ncbi.nlm.nih.gov/pubmed/28742087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005765
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