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Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice

Scrub typhus is a neglected, but important, tropical disease, which puts one-third of the world's population at risk. The disease is caused by Orientia tsutsugamushi, an obligately intracellular Gram-negative bacterium. Dysregulation in immune responses is known to contribute to disease pathoge...

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Detalhes bibliográficos
Main Authors: Soong, Lynn, Wang, Hui, Shelite, Thomas R., Liang, Yuejin, Mendell, Nicole L., Sun, Jiaren, Gong, Bin, Valbuena, Gustavo A., Bouyer, Donald H., Walker, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177881/
https://ncbi.nlm.nih.gov/pubmed/25254971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003191
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