Lataa...
Inhibition of caspase-1 or gasdermin-D enable caspase-8 activation in the Naip5/NLRC4/ASC inflammasome
Legionella pneumophila is a Gram-negative, flagellated bacterium that survives in phagocytes and causes Legionnaires’ disease. Upon infection of mammalian macrophages, cytosolic flagellin triggers the activation of Naip/NLRC4 inflammasome, which culminates in pyroptosis and restriction of bacterial...
Tallennettuna:
| Julkaisussa: | PLoS Pathog |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2017
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5542441/ https://ncbi.nlm.nih.gov/pubmed/28771586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006502 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|