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Perturbed Mucosal Immunity and Dysbiosis Accompany Clinical Disease in a Rat Model of Spondyloarthritis

OBJECTIVE: The HLA-B27/β2 microglobulin (β2m) transgenic rat is a leading model of B27-associated spondyloarthopathy and disease is dependent on the presence of intestinal bacteria. We have shown previously that adult HLA-B27/β2m rats have an altered intestinal microbiota. In this study we sought to...

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Detaylı Bibliyografya
Yayımlandı:Arthritis Rheumatol
Asıl Yazarlar: Asquith, Mark, Stauffer, Patrick, Davin, Sean, Mitchell, Claire, Lin, Phoebe, Rosenbaum, James T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542398/
https://ncbi.nlm.nih.gov/pubmed/26992013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39681
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