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Effects of HLA-B27 on Gut Microbiota in Experimental Spondyloarthritis Implicate an Ecological Model of Dysbiosis

OBJECTIVES: We investigated whether HLA-B27-mediated experimental spondyloarthritis (SpA) is associated with a common gut microbial signature to identify potential drivers of pathogenesis. METHODS: Effects of HLA-B27 on three genetic backgrounds, Dark Agouti (DA), Lewis, and Fischer were compared, u...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Gill, Tejpal, Asquith, Mark, Brooks, Stephen R., Rosenbaum, James T., Colbert, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101666/
https://ncbi.nlm.nih.gov/pubmed/29287307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40405
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