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Novel Inter-omic Analysis Reveals Relationships Between Diverse Gut Microbiota and Host Immune Dysregulation in HLA-B27-Induced Experimental Spondyloarthritis

SUMMARY: OBJECTIVE: To define inflammation-related host-microbe interactions in experimental spondyloarthritis using novel inter-omic approaches. METHODS: The relative frequency of gut microbes was determined by 16S rRNA gene sequencing, and gene expression by RNA-seq of host tissue. HLA-B27/human β...

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Publicado no:Arthritis Rheumatol
Main Authors: Gill, Tejpal, Brooks, Stephen R., Rosenbaum, James T., Asquith, Mark, Colbert, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603391/
https://ncbi.nlm.nih.gov/pubmed/31216122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41018
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