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Changes in the nuclear distribution of cyclin (PCNA) but not its synthesis depend on DNA replication.

Synthesis of cyclin in serum-stimulated quiescent 3T3 cells increases shortly before DNA synthesis after 10 h of stimulation, reaching a maximum after 16 h. Inhibition of DNA synthesis by hydroxyurea does not affect the increase of cyclin following stimulation, as determined by quantitative two-dime...

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Detalles Bibliográficos
Main Authors: Bravo, R, Macdonald-Bravo, H
Formato: Artigo
Idioma:Inglês
Publicado: 1985
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC554238/
https://ncbi.nlm.nih.gov/pubmed/2861088
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