MicroRNA-145 down-regulates mucin 5AC to alleviate airway remodeling and targets EGFR to inhibit cytokine expression

This study aims to explore how microRNA-145 (miR-145) affects airway remodeling and cytokine expression by targeting epidermal growth factor receptor (EGFR) to regulate mucin 5AC (MUC5AC). Mice alveolar epithelial cells (AECs) were divided into a control, blank, miR-145 mimics, mimic control, miR-14...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cheng, Zhe, Dai, Ling-Ling, Wang, Xi, Jia, Liu-Qun, Jing, Xiao-Gang, Li, Peng-Fei, Liu, Meng, Wang, Huan, An, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542269/
https://ncbi.nlm.nih.gov/pubmed/28564633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17933
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