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Role for mucin-5AC in upper and lower airway pathogenesis in mice

Mucin-5AC (MUC5AC) is a major secreted mucin in pathogenic airways. To determine its role in mucus-related airway disorders, Muc5ac-deficient (Muc5ac(−/−)) and wild-type (Muc5ac(+/+)) mice were compared in bleomycin-induced pulmonary fibrosis, respiratory syncytial virus (RSV) disease, and ozone tox...

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Detalhes bibliográficos
Publicado no:Toxicol Pathol
Main Authors: Cho, Hye-Youn, Park, Soojung, Miller, Laura, Lee, Huei-Chen, Langenbach, Robert, Kleeberger, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195843/
https://ncbi.nlm.nih.gov/pubmed/33938323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/01926233211004433
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