Clinically significant sub-clonality for common drivers can be detected in 26% of KRAS/EGFR mutated lung adenocarcinomas

Genetic sub-clonality has been described in multiple malignancies, however the presence of sub-clonality for major drivers in lung adenocarcinoma and its clinical significance is a subject under debate. Using molecular and morphometric approach, 347 lung adenocarcinoma samples were analyzed for KRAS...

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Vydáno v:Oncotarget
Hlavní autoři: Simon, Einav, Bick, Tova, Sarji, Shada, Shentzer, Talia, Prinz, Elad, Yehiam, Liza, Sabo, Edmond, Ben-Izhak, Ofer, Hershkovitz, Dov
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542222/
https://ncbi.nlm.nih.gov/pubmed/28501852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17399
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