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Characterization of Factors Affecting the Detection Limit of EGFR p.T790M in Circulating Tumor DNA

OBJECTIVE: Circulating tumor DNA is a promising noninvasive tool for cancer monitoring. One of the challenges in applying this tool is the detection of low-frequency mutations. The detection limit of these mutations varies between different molecular methods. The aim of this study is to characterize...

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Publicat a:Technol Cancer Res Treat
Autors principals: Fahoum, Ibrahim, Forer, Relly, Volodarsky, Dina, Vulih, Inna, Bick, Tova, Sarji, Shada, Bamberger, Zeev, Ben-Izhak, Ofer, Sabo, Edmond, Hershberg, Ruth, Hershkovitz, Dov
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090485/
https://ncbi.nlm.nih.gov/pubmed/30099961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1533033818793653
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