Arsenic trioxide and angiotensin II have inhibitory effects on HERG protein expression: Evidence for the role of PML SUMOylation

The human ether-a-go-go-related gene (HERG) channel is a novel target for the treatment of drug-induced long QT syndrome, which causes lethal cardiotoxicity. This study is designed to explore the possible role of PML SUMOylation and its associated nuclear bodies (NBs) in the regulation of HERG prote...

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Udgivet i:Oncotarget
Main Authors: Liu, Yu, Li, Duo, Nie, Dan, Liu, Shang-Kun, Qiu, Fang, Liu, Mei-Tong, Li, Yuan-Yuan, Wang, Jia-Xin, Liu, Yan-Xin, Dong, Chang-Jiang, Wu, Di, Tian, Wei, Yang, Jia, Mu, Wei, Li, Jia-Tong, Zhao, Dan, Wang, Xiao-Feng, Chu, Wen-Feng, Yang, Bao-Feng
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542199/
https://ncbi.nlm.nih.gov/pubmed/28525371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17563
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