Arsenic trioxide and angiotensin II have inhibitory effects on HERG protein expression: Evidence for the role of PML SUMOylation

The human ether-a-go-go-related gene (HERG) channel is a novel target for the treatment of drug-induced long QT syndrome, which causes lethal cardiotoxicity. This study is designed to explore the possible role of PML SUMOylation and its associated nuclear bodies (NBs) in the regulation of HERG prote...

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Pubblicato in:Oncotarget
Autori principali: Liu, Yu, Li, Duo, Nie, Dan, Liu, Shang-Kun, Qiu, Fang, Liu, Mei-Tong, Li, Yuan-Yuan, Wang, Jia-Xin, Liu, Yan-Xin, Dong, Chang-Jiang, Wu, Di, Tian, Wei, Yang, Jia, Mu, Wei, Li, Jia-Tong, Zhao, Dan, Wang, Xiao-Feng, Chu, Wen-Feng, Yang, Bao-Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542199/
https://ncbi.nlm.nih.gov/pubmed/28525371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17563
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