Manipulating PML SUMOylation via Silencing UBC9 and RNF4 Regulates Cardiac Fibrosis

The promyelocytic leukemia protein (PML) is essential in the assembly of dynamic subnuclear structures called PML nuclear bodies (PML-NBs), which are involved in regulating diverse cellular functions. However, the possibility of PML being involved in cardiac disease has not been examined. In mice un...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Liu, Yu, Zhao, Dan, Qiu, Fang, Zhang, Ling-Ling, Liu, Shang-Kun, Li, Yuan-Yuan, Liu, Mei-Tong, Wu, Di, Wang, Jia-Xin, Ding, Xiao-Qing, Liu, Yan-Xin, Dong, Chang-Jiang, Shao, Xiao-Qi, Yang, Bao-Feng, Chu, Wen-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363217/
https://ncbi.nlm.nih.gov/pubmed/28143738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.12.021
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