Triptolide mitigates radiation-induced pneumonitis via inhibition of alveolar macrophages and related inflammatory molecules

Ionizing radiation-induced pulmonary injury is a major limitation of radiotherapy for thoracic tumors. We have demonstrated that triptolide (TPL) could alleviate IR-induced pneumonia and pulmonary fibrosis. In this study, we explored the underlying mechanism by which TPL mitigates the effects of rad...

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Publicado en:Oncotarget
Autores principales: Chen, Chun, Yang, Shanmin, Zhang, Mei, Zhang, Zhenhuan, Zhang, Steven B., Wu, Bing, Hong, Jinsheng, Zhang, Weijian, Lin, Jianhua, Okunieff, Paul, Zhang, Lurong
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542172/
https://ncbi.nlm.nih.gov/pubmed/28415830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16456
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