Renin-Angiotensin System Suppression Mitigates Experimental Radiation Pneumonitis

PURPOSE: To find mitigators of pneumonitis induced by moderate doses of thoracic radiation (10–15 Gy). MATERIALS AND METHODS: Unanesthetized WAG/RijCmcr female rats received single doses of X-irradiation (10, 12 or 15 Gy at 1.615 Gy/minute) to the thorax. Captopril (an angiotensin converting enzyme...

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Hauptverfasser: Ghosh, Swarajit N., Zhang, Rong, Fish, Brian L., Semenenko, Vladimir A., Li, X. Allen, Moulder, John E., Jacobs, Elizabeth R., Medhora, Meetha
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800372/
https://ncbi.nlm.nih.gov/pubmed/19931735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2009.07.1743
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