Triptolide mitigates radiation-induced pulmonary fibrosis via inhibition of axis of alveolar macrophages-NOXes-ROS-myofibroblasts

Purpose: IR-induced pulmonary fibrosis is one of the most severe late complications of radiotherapy for lung cancer. It is urgently needed to discover a new drug for anti-IR lung fibrosis. Our previous studies have indicated that TPL exhibits both anti-IR lung fibrosis and anti-tumor activities. To...

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Опубликовано в: :Cancer Biol Ther
Главные авторы: Chen, Chun, Yang, Shanmin, Zhang, Mei, Zhang, Zhenhuan, Hong, Jingshen, Han, Deping, Ma, Jun, Zhang, Steven B., Okunieff, Paul, Zhang, Lurong
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910907/
https://ncbi.nlm.nih.gov/pubmed/27003327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1139229
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