Impaired coronary metabolic dilation in the metabolic syndrome is linked to mitochondrial dysfunction and mitochondrial DNA damage

Mitochondrial dysfunction in obesity and diabetes can be caused by excessive production of free radicals, which can damage mitochondrial DNA. Because mitochondrial DNA plays a key role in the production of ATP necessary for cardiac work, we hypothesized that mitochondrial dysfunction, induced by mit...

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Bibliografski detalji
Izdano u:Basic Res Cardiol
Glavni autori: Guarini, Giacinta, Kiyooka, Takahiko, Ohanyan, Vahagn, Pung, Yuh Fen, Marzilli, Mario, Chen, Yeong Renn, Chen, Chwen Lih, Kang, Patrick T., Hardwick, James P., Kolz, Christopher L., Yin, Liya, Wilson, Glenn L., Shokolenko, Inna, Dobson, James G., Fenton, Richard, Chilian, William M.
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542063/
https://ncbi.nlm.nih.gov/pubmed/27040114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-016-0547-4
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