Impaired coronary metabolic dilation in the metabolic syndrome is linked to mitochondrial dysfunction and mitochondrial DNA damage

Mitochondrial dysfunction in obesity and diabetes can be caused by excessive production of free radicals, which can damage mitochondrial DNA. Because mitochondrial DNA plays a key role in the production of ATP necessary for cardiac work, we hypothesized that mitochondrial dysfunction, induced by mit...

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Detaylı Bibliyografya
Yayımlandı:Basic Res Cardiol
Asıl Yazarlar: Guarini, Giacinta, Kiyooka, Takahiko, Ohanyan, Vahagn, Pung, Yuh Fen, Marzilli, Mario, Chen, Yeong Renn, Chen, Chwen Lih, Kang, Patrick T., Hardwick, James P., Kolz, Christopher L., Yin, Liya, Wilson, Glenn L., Shokolenko, Inna, Dobson, James G., Fenton, Richard, Chilian, William M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542063/
https://ncbi.nlm.nih.gov/pubmed/27040114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-016-0547-4
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