Resolution of Mitochondrial Oxidative Stress Rescues Coronary Collateral Growth in Zucker Obese Fatty Rats

OBJECTIVE: We have previously found abrogated ischemia-induced coronary collateral growth in Zucker obese fatty rats (ZOF) compared to Zucker lean rats (ZLN). Because ZOF have structural abnormalities in their mitochondria suggesting dysfunction, and also show increased production of O(2)ׄ(−), we hy...

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Autors principals: Pung, Yuh Fen, Rocic, Petra, Murphy, Michael P, Smith, Robin A J, Hafemeister, Jennifer, Ohanyan, Vahagn, Guarini, Giacinta, Yin, Liya, Chilian, William M
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013346/
https://ncbi.nlm.nih.gov/pubmed/22155454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.241802
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