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Fluorinated Amine Stereotriads via Allene Amination

The incorporation of fluorine into organic scaffolds often improves the bioactivity of pharmaceutically relevant compounds. C–F/C–N/C–O stereotriad motifs are prevalent in antivirals, neuraminidase inhibitors, and modulators of androgen receptors, but are challenging to install. An oxidative allene...

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Dades bibliogràfiques
Publicat a:Org Lett
Autors principals: Liu, Lu, Gerstner, Nels C., Oxtoby, Lucas J., Guzei, Ilia A., Schomaker, Jennifer M.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541934/
https://ncbi.nlm.nih.gov/pubmed/28573862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01342
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