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Oxidative Allene Amination for the Synthesis of Azetidin-3-ones

Regioselectivity in the aziridination of silyl-substituted homoallenic sulfamates is readily diverted to the distal double bond of the allene to yield endocyclic bicyclic methyleneaziridines with excellent stereocontrol. Subsequent reaction with electrophilic oxygen sources initiates facile rearrang...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Burke, Eileen G., Schomaker, Jennifer M.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701577/
https://ncbi.nlm.nih.gov/pubmed/26387687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201504723
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