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Consequences of frameshift mutations at the immunoglobulin heavy chain locus of the mouse.

From an IgM secreting hybridoma line we have isolated 16 spontaneous mutants that produce truncated IgM polypeptides. The size of the mu-mRNAs produced by these mutants is normal, but they express 3- to 100-fold less mu-mRNA and mutant mu-protein than the parental cell line. Nucleotide sequence anal...

詳細記述

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書誌詳細
出版年:EMBO J
主要な著者: Baumann, B, Potash, M J, Köhler, G
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 1985
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554193/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3926482/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1985.tb03636.x
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