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Immunoglobulin heavy chain locus of the rat: striking homology to mouse antibody genes.

DNA encoding the rat diversity segment (D), joining segment (JH), and constant (C) region mu, gamma 2a, gamma 1, gamma 2b, epsilon and alpha of the Ig heavy chain has been isolated from a cosmid library. Restriction mapping allowed us to identify two gene clusters: D-JH-C mu and C gamma 1-C gamma 2b...

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Detalhes bibliográficos
Main Authors: Brüggemann, M, Free, J, Diamond, A, Howard, J, Cobbold, S, Waldmann, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC386441/
https://ncbi.nlm.nih.gov/pubmed/3016742
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