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phydms: software for phylogenetic analyses informed by deep mutational scanning

It has recently become possible to experimentally measure the effects of all amino-acid point mutations to proteins using deep mutational scanning. These experimental measurements can inform site-specific phylogenetic substitution models of gene evolution in nature. Here we describe software that ef...

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Détails bibliographiques
Publié dans:PeerJ
Auteurs principaux: Hilton, Sarah K., Doud, Michael B., Bloom, Jesse D.
Format: Artigo
Langue:Inglês
Publié: PeerJ Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541924/
https://ncbi.nlm.nih.gov/pubmed/28785526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3657
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