GLP-1 acts on habenular avoidance circuits to control nicotine intake

Tobacco smokers titrate their nicotine intake to avoid its noxious effects, sensitivity to which may influence vulnerability to tobacco dependence, yet mechanisms of nicotine avoidance are poorly understood. Here, we show that nicotine activates glucagon-like peptide-1 (GLP-1) neurons in the nucleus...

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Publicat a:Nat Neurosci
Autors principals: Tuesta, Luis M., Chen, Zuxin, Duncan, Alexander, Fowler, Christie D., Ishikawa, Masago, Lee, Brian R., Liu, Xin-An, Lu, Qun, Cameron, Michael, Hayes, Matthew R., Kamenecka, Theodore M., Pletcher, Matthew, Kenny, Paul J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541856/
https://ncbi.nlm.nih.gov/pubmed/28368384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4540
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