GLP-1 acts on habenular avoidance circuits to control nicotine intake

Tobacco smokers titrate their nicotine intake to avoid its noxious effects, sensitivity to which may influence vulnerability to tobacco dependence, yet mechanisms of nicotine avoidance are poorly understood. Here, we show that nicotine activates glucagon-like peptide-1 (GLP-1) neurons in the nucleus...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Tuesta, Luis M., Chen, Zuxin, Duncan, Alexander, Fowler, Christie D., Ishikawa, Masago, Lee, Brian R., Liu, Xin-An, Lu, Qun, Cameron, Michael, Hayes, Matthew R., Kamenecka, Theodore M., Pletcher, Matthew, Kenny, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541856/
https://ncbi.nlm.nih.gov/pubmed/28368384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4540
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