GLP-1 acts on habenular avoidance circuits to control nicotine intake

Tobacco smokers titrate their nicotine intake to avoid its noxious effects, sensitivity to which may influence vulnerability to tobacco dependence, yet mechanisms of nicotine avoidance are poorly understood. Here, we show that nicotine activates glucagon-like peptide-1 (GLP-1) neurons in the nucleus...

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Bibliografiske detaljer
Udgivet i:	Nat Neurosci
Main Authors:	Tuesta, Luis M., Chen, Zuxin, Duncan, Alexander, Fowler, Christie D., Ishikawa, Masago, Lee, Brian R., Liu, Xin-An, Lu, Qun, Cameron, Michael, Hayes, Matthew R., Kamenecka, Theodore M., Pletcher, Matthew, Kenny, Paul J.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2017
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5541856/ https://ncbi.nlm.nih.gov/pubmed/28368384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4540
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GLP-1 acts on habenular avoidance circuits to control nicotine intake

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